Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 36 (5), 716-722

Patients With Cervical Ureaplasma Urealyticum and Chlamydia Trachomatis Infection Undergoing IVF/ICSI-ET: The Need for New Paradigm

Affiliations

Patients With Cervical Ureaplasma Urealyticum and Chlamydia Trachomatis Infection Undergoing IVF/ICSI-ET: The Need for New Paradigm

Qing-Zhen Xie et al. J Huazhong Univ Sci Technolog Med Sci.

Abstract

Genital tract infections with ureaplasma urealyticum (UU) and chlamydia trachomatis (CT) are the most frequent sexually-transmitted disease worldwide. UU and CT infections are considered to be the leading cause for infertility and adverse pregnancy outcomes. However, little is known about the specific effect of cervical UU and CT infections on the etiology of female infertility, as well as the pregnancy outcomes of the patients undergoing in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET). In order to find the association between cervical UU and/or CT infection and pregnancy outcomes, we conducted a retrospective case-control study on the patients undergoing IVF/ICSI-ET with cervical UU and/or CT infection. A total of 2208 patients who received IVF/ICSI-ET were enrolled in this study. Data on the general conditions, pregnancy history and clinical pregnant outcomes were analyzed in terms of the cervical UU and CT detection. Our results revealed that cervical UU and CT infections were the risk factors for ectopic pregnancy and tubal factor-induced infertility. Moreover, the pregnancy rate, abortion rate, ectopic pregnancy rate and premature birth rate in patients with UU and/or CT infections showed no significant difference when compared with the control group. We recommend that cervical UU and CT detection should be an optional item for infertility patients and clinical UU detection should differentiate the subtypes of cervical UU. Positive cervical UU and CT infections should not be taken as strict contraindications for IVF/ICSI-ET.

Keywords: chlamydia trachomatis; infertility; pregnancy outcomes; ureaplasma urealyticum.

Similar articles

See all similar articles

Cited by 1 article

References

    1. Eur J Contracept Reprod Health Care. 2013 Feb;18(1):68-74 - PubMed
    1. Ginekol Pol. 2012 Nov;83(11):819-21 - PubMed
    1. New Microbiol. 2010 Jan;33(1):69-76 - PubMed
    1. Gynecol Obstet Fertil. 2004 Feb;32(2):135-9 - PubMed
    1. Int J STD AIDS. 2014 Mar;25(4):294-8 - PubMed

LinkOut - more resources

Feedback