Controversies in Persistent (Chronic) Lyme Disease

J Infus Nurs. 2016 Nov/Dec;39(6):369-375. doi: 10.1097/NAN.0000000000000195.


The Centers for Disease Control and Prevention estimates that more than 300 000 new cases of Lyme disease occur each year in the United States and that 10% to 20% of these patients will remain symptomatic despite receiving appropriate antibiotic therapy. Many elements of the disease are poorly understood and have generated considerable controversy. This paper discusses the medical controversies related to posttreatment manifestations and their potential impact on infusion nurses.

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Borrelia burgdorferi*
  • Chronic Disease
  • Drug Administration Schedule
  • Humans
  • Lyme Disease / diagnosis
  • Lyme Disease / drug therapy*
  • Nurse's Role
  • United States


  • Anti-Bacterial Agents