Breast Cancer and Deodorants/Antiperspirants: a Systematic Review

Cent Eur J Public Health. 2016 Sep;24(3):245-247. doi: 10.21101/cejph.a4475.


Background: Over the last decade, the possible association between underarm deodorants/ antiperspirants use and breast cancer risk has raised important interest in the scientific community. The objective of our systematic review is to estimate the pooled risk of deodorants/antiperspirants use for breast cancer.

Methods: All observational studies that evaluated the association between breast cancer risk and deodorants/antiperspirants use were reviewed. We have only identified two case-control studies, carried out between 2002 and 2006.

Results: The first study was conducted in USA and investigated the possible relationship between use of products applied for underarm perspiration and the risk for breast cancer in women aged 20-74 years. This population-based case-control study gathered information by in-person interview. The second study was conducted in Iraq and investigated the possible relationship between use of antiperspirants and the risk for breast cancer in women attending a teaching hospital. This study also gathered information by in-person interview. There was no risk of antiperspirants use in the pooled risk (odds ratio 0.40, 95% confidence interval 0.35-0.46).

Conclusion: Our comprehensive search has identified an insufficient number of studies to conduct a quantitative review and obtain reliable results. Further prospective studies are strongly needed.

Keywords: Cancer; antiperspirants; breast; case-control; cohort; deodorants; meta-analysis; systematic review.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Aluminum Compounds / adverse effects
  • Antiperspirants / adverse effects*
  • Antiperspirants / chemistry
  • Breast Neoplasms / chemically induced*
  • Breast Neoplasms / pathology
  • Deodorants / adverse effects*
  • Deodorants / chemistry
  • Female
  • Humans
  • Parabens / adverse effects
  • Risk Factors


  • Aluminum Compounds
  • Antiperspirants
  • Deodorants
  • Parabens