Comparison of open-access vancomycin dosing websites

J Clin Pharm Ther. 2017 Apr;42(2):128-131. doi: 10.1111/jcpt.12466. Epub 2016 Oct 18.


What is known and objective: There are many methods for dosing vancomycin. The purpose of this commentary was to compare open-access vancomycin dosing websites with and describe how body weight can affect their pharmacokinetic (PK) calculations.

Comment: A vancomycin dosing website,, was developed to improve the dosing practice at our health system. Nine other vancomycin dosing calculators were identified, including three open-access websites. Each website uses a different dosing method. Most of the websites calculated similar doses for patients with normal body weight. was the only website to calculate practical doses for obese patients, and it calculated higher daily doses for underweight patients compared to other websites.

What is new and conclusion: is an open-access vancomycin dosing website that was developed using the Bauer PK method. Compared with three other websites, PK calculations resulted in significant differences for underweight and obese patients.

Keywords: Calculator; Dosing; Pharmacokinetics; Vancomycin; Website.

Publication types

  • Comparative Study

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Area Under Curve
  • Humans
  • Internet
  • Vancomycin / administration & dosage*
  • Vancomycin / pharmacokinetics


  • Anti-Bacterial Agents
  • Vancomycin