Imaging of Paget's disease of bone

Wien Med Wochenschr. 2017 Feb;167(1-2):9-17. doi: 10.1007/s10354-016-0517-3. Epub 2016 Oct 19.

Abstract

Paget's disease of bone is a disorder of bone remodelling, leading to changes in the architecture and overall appearance of the bone. The disorder may be monostotic or polyostotic and affect any bone in the body, although most commonly it involves the spine, pelvis, skull and femur. This article explores the different imaging modalities used in the assessment of Paget's disease of bone in its different phases. The relative merits of each imaging modality is discussed with illustrative examples, in particular with respect to radiographs, nuclear medicine bone scan, computed tomography (CT) and magnetic resonance imaging (MRI).

Keywords: CT; MRI; Nuclear medicine bone scan; Paget’s disease; Radiographs.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Bone and Bones / diagnostic imaging
  • Humans
  • Magnetic Resonance Imaging
  • Osteitis Deformans / complications
  • Osteitis Deformans / diagnostic imaging*
  • Osteitis Deformans / pathology
  • Radionuclide Imaging
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed