Single Anastomosis Sleeve Ileal Bypass: New Step in the Evolution of Bariatric Surgeries

J Invest Surg. 2017 Oct;30(5):291-296. doi: 10.1080/08941939.2016.1241841. Epub 2016 Oct 21.


Purpose: Single anastomosis sleeve ileal bypass (SASI) procedure appears as a new metabolic and bariatric surgery based on Santoro's operation, in which a sleeve gastrectomy is followed by a side-to-side gastroileal anastomosis. The study is aimed to evaluate the short-term outcomes of laparoscopic single anastomosis sleeve ileal bypass with respect to postoperative weight loss and metabolic and nutritional effects on patients.

Methods: Forty-five morbidly obese patients with a mean age of 31.2 years and a mean body mass index (BMI) of 43.2 kg/m2 underwent SASI bypass. Postoperatively, all patients were followed up at 1, 3, 6, and 12 months, and during each visit data about their BMI, obesity-related comorbidities, and nutritional status were collected.

Results: One year after the surgery, mean BMI decreased to 29.1 kg/m2 and there was significant decrease in plasma level of fasting blood glucose, insulin, and low-density lipoprotein. On the other hand, there was significant increase in high-density lipoprotein plasma level, whereas hemoglobin and albumin plasma level remained normal. Six months after the surgery, calcium plasma level showed mild decrease in two cases, which was improved with multivitamin tablets. In 93% of our patients, multivitamin supplements were stopped after six months of surgery.

Conclusions: Laparoscopic SASI bypass has been shown to be an effective, safe, and simple procedure for the treatment of morbid obesity and its associated metabolic consequences. Moreover, it results in minimal postoperative nutritional complications in comparison to other bariatric procedures.

Keywords: metabolic surgery; new bariatric surgery; single anastomosis sleeve ileal bypass; sleeve gastrectomy.

MeSH terms

  • Adult
  • Bariatric Surgery / methods*
  • Bariatric Surgery / statistics & numerical data
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obesity, Morbid / surgery*
  • Young Adult