Education as a predictor of antidepressant and anxiolytic medication use after bereavement: a population-based record linkage study

Qual Life Res. 2017 May;26(5):1251-1262. doi: 10.1007/s11136-016-1440-1. Epub 2016 Oct 21.

Abstract

Purpose: Educational attainment has been shown to be positively associated with mental health and a potential buffer to stressful events. One stressful life event likely to affect everyone in their lifetime is bereavement. This paper assesses the effect of educational attainment on mental health post-bereavement.

Methods: By utilising large administrative datasets, linking Census returns to death records and prescribed medication data, we analysed the bereavement exposure of 208,332 individuals aged 25-74 years. Two-level multi-level logistic regression models were constructed to determine the likelihood of antidepressant medication use (a proxy of mental ill health) post-bereavement given level of educational attainment.

Results: Individuals who are bereaved have greater antidepressant use than those who are not bereaved, with over a quarter (26.5 %) of those bereaved by suicide in receipt of antidepressant medication compared to just 12.4 % of those not bereaved. Within individuals bereaved by a sudden death, those with a university degree or higher qualifications are 73 % less likely to be in receipt of antidepressant medication compared to those with no qualifications, after full adjustment for demographic, socio-economic and area factors (OR 0.27, 95 % CI 0.09,0.75). Higher educational attainment and no qualifications have an equivalent effect for those bereaved by suicide.

Conclusions: Education may protect against poor mental health, as measured by the use of antidepressant medication, post-bereavement, except in those bereaved by suicide. This is likely due to the improved cognitive, personal and psychological skills gained from time spent in education.

Keywords: Administrative data; Antidepressant; Bereavement; Education; Mental health; Suicide.

MeSH terms

  • Adult
  • Aged
  • Anti-Anxiety Agents / therapeutic use*
  • Antidepressive Agents / therapeutic use*
  • Bereavement*
  • Female
  • Humans
  • Life Change Events
  • Male
  • Medical Record Linkage / methods*
  • Middle Aged
  • Patient Education as Topic / methods*
  • Quality of Life / psychology*

Substances

  • Anti-Anxiety Agents
  • Antidepressive Agents