Fine-needle aspiration biopsy of prostate synovial sarcoma: A case report and review of the literature

Diagn Cytopathol. 2017 Feb;45(2):168-172. doi: 10.1002/dc.23623. Epub 2016 Oct 24.


We describe a case of synovial sarcoma originating from prostate gland. The diagnosis was confirmed by fluorescent in situ hybridization analysis (FISH) for SYT rearrangement on the cell block. Synovial sarcoma is a high grade soft tissue malignancy with exceedingly rare involvement of genitourinary tract. However this entity should be considered in the differential diagnosis when dealing with aspiration biopsies of particularly deep seated lesions with spindle cell or small round blue cell cytomorphology. Diagn. Cytopathol. 2017;45:168-172. © 2016 Wiley Periodicals, Inc.

Keywords: fine-needle aspiration (FNA); fluorescent in situ hybridization (FISH); prostate gland; synovial sarcoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Biopsy, Fine-Needle
  • Diagnosis, Differential
  • Humans
  • Male
  • Prostatic Neoplasms / diagnostic imaging
  • Prostatic Neoplasms / pathology*
  • Sarcoma, Synovial / diagnostic imaging
  • Sarcoma, Synovial / pathology*