The Relief Effects of Ramelteon on Refractory Chronic Migraine: A Case Report

Clin Psychopharmacol Neurosci. 2016 Nov 30;14(4):405-406. doi: 10.9758/cpn.2016.14.4.405.


The selective melatonin receptor agonism effect of ramelteon is useful for insomnia. Here we wanted to present a refractory chronic migraine case, who had significant improvements in migraine after using ramelteon. The possible mechanism for the ramelteon in the migraine relief might be related to melatonin effects.

Keywords: Migraine disorders; Ramelteon; Sleep wake disorders.

Publication types

  • Case Reports