Abstract
In this article, I review how an RNA restriction enzyme, a highly sequence-specific endoribonuclease, was for the first time discovered in 2003 and how the concept of RNA interference using RNA restriction enzymes or mRNA interferases has been developed.
Keywords:
E. coli; RNA interference; RNA restriction enzymes; Single-Protein Production (SPP).
Copyright © 2016 Elsevier B.V. All rights reserved.
MeSH terms
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DNA-Binding Proteins / chemistry
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DNA-Binding Proteins / genetics
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DNA-Binding Proteins / metabolism*
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Endoribonucleases / chemistry
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Endoribonucleases / genetics
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Endoribonucleases / metabolism*
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Escherichia coli Proteins / chemistry
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Escherichia coli Proteins / genetics
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Escherichia coli Proteins / metabolism*
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Protein Biosynthesis / genetics*
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RNA Interference*
Substances
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DNA-Binding Proteins
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Escherichia coli Proteins
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MazE protein, E coli
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MazF protein, E coli
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Endoribonucleases