Ornidazole-induced fixed drug reaction on sole: case report and review of the literature

Cutan Ocul Toxicol. 2017 Sep;36(3):294-296. doi: 10.1080/15569527.2016.1249796. Epub 2016 Nov 23.


Background: Fixed drug eruption (FDE) is a special variant of drug reaction seen on skin or mucous membrane, and typically recurs at the same location. Ornidazole-induced FDE cases have been reported extremely rare.

Case: The 48-year-old female patient was diagnosed for ornidazole-induced fixed drug reaction on the sole. The patient's history revealed that the lesion occurred for the third time in the last 6 months and she was administered ornidazole tablet 3 times by the gynecologist for genitourinary tract infection.

Conclusion: This report presents a case of fixed drug reaction located at the sole induced by ornidazole use and a literature review.

Keywords: Fix drug eruption; ornidazole; sole.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antitrichomonal Agents / adverse effects*
  • Antitrichomonal Agents / therapeutic use
  • Drug Eruptions / etiology*
  • Drug Eruptions / pathology
  • Female
  • Humans
  • Middle Aged
  • Ornidazole / adverse effects*
  • Ornidazole / therapeutic use
  • Skin / drug effects
  • Skin / pathology
  • Urinary Tract Infections / drug therapy


  • Antitrichomonal Agents
  • Ornidazole