A presumptive case of gluten sensitivity in a border terrier: a multisystem disorder?

Vet Rec. 2016 Dec 3;179(22):573. doi: 10.1136/vr.103910. Epub 2016 Oct 26.


Paroxysmal gluten-sensitive dyskinesia (previously termed canine epileptoid cramping syndrome) is a condition of Border terriers in which the leading manifestation is neurological. The authors describe a case they believe to represent the first report of a Border terrier with a combination of neurological signs, atopy, positive serological results for anti-transglutaminase 2 (TG2 IgA) and anti-gliadin (AGA IgG) antibodies, and signs suggestive of gastrointestinal disease with pathological changes in the gastrointestinal tract-seemingly responsive to a gluten-free diet. As such, the authors suggest that gluten sensitivity in Border terriers may manifest as a multisystem disease in a similar manner to that seen in human beings.

Keywords: Atopy; Dermatology; Dyskinesia; Inflammatory Bowel Disease; Neurology.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Dog Diseases / chemically induced*
  • Dog Diseases / diagnosis
  • Dogs
  • Food Hypersensitivity / diagnosis
  • Food Hypersensitivity / veterinary*
  • Glutens / adverse effects*
  • Male


  • Glutens