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Case Reports
. 2012 Apr;5(2):67-70.
doi: 10.4021/gr403w. Epub 2012 Mar 20.

A Flare of Ulcerative Colitis Accompanied With Cerebral Sinus Venous Thrombosis And Bilateral Thalamic Infarctus: A Case Report

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Free PMC article
Case Reports

A Flare of Ulcerative Colitis Accompanied With Cerebral Sinus Venous Thrombosis And Bilateral Thalamic Infarctus: A Case Report

Ahmet Cumhur Dulger et al. Gastroenterology Res. .
Free PMC article

Abstract

Ulcerative colitis (UC) is a chronic inflammatory and recurrent disorder that is characterized by bowel inflammation. Some patients with Inflammatory Bowel Disease (IBD) have acute, severe, and sometimes devastating intracranial complications that require immediate medical intervention. Cerebral sinus vein thrombosis is a rare but serious extraintestinal complication associated with ulcerative colitis. Herein we report a 30-year-old man with UC who presented with a flare of gastrointestinal symptoms with mental obtundation and apathy. Total colonoscopy revealed active colitis and cranial MRI showed extensive cerebral sinus venous thrombosis with thalamic infarcts. Because the patient was clinically unstable metilprednisolon with low molecular weight heparin were administered. Two days after treatment the patient was died despite all medical efforts.

Keywords: Sinus vein thrombosis; Thalamic infarcts; Ulcerative colitis.

Figures

Figure 1
Figure 1
Distal colonoscopy of the patient showed mucosal hyperemia with multiple ulcers.
Figure 2
Figure 2
MRI of the cranium revealed infarct areas of posterior limb of capsula interna, right globus pallidus, left occipital lobe and bilateral thalamus.
Figure 3
Figure 3
Cerebral venous MR angio showed massive thrombosis of sinus rectus, left transvers and sigmoid sinuses.

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