Skin autofluorescence is increased in young people with type 1 diabetes exposed to secondhand smoking

J Diabetes. 2017 Mar;9(3):308-310. doi: 10.1111/1753-0407.12498. Epub 2016 Dec 1.


Skin autofluorescence is increased in diabetes, rises with age, and predicts diabetes-related complications. Exposure to secondhand smoke, because one or more family members are smokers, further increases skin autofluorescence in children and young adults with type 1 diabetes. Elimination of passive smoking should be a goal in diabetes education. Association between age and skin autofluorescence (SAF), in arbitrary units (AU), in young people with type 1 diabetes exposed (black dots) and not exposed (open dots) to secondhand smoke. Regression lines show correlations between these parameters in exposed (solid line) and not exposed (dashed line) patients.

Keywords: autofluorescence; glycation; smoking.

Publication types

  • Letter

MeSH terms

  • Adolescent
  • Child
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetic Angiopathies / diagnosis
  • Diabetic Angiopathies / etiology
  • Diabetic Angiopathies / metabolism
  • Female
  • Fluorescence
  • Glycation End Products, Advanced / metabolism*
  • Humans
  • Male
  • Risk Factors
  • Skin / metabolism*
  • Tobacco Smoke Pollution*
  • Young Adult


  • Glycation End Products, Advanced
  • Tobacco Smoke Pollution