Sweetened Soft Drinks Consumption Is Associated with Metabolic Syndrome: Cross-sectional Analysis from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)

J Am Coll Nutr. 2017 Feb;36(2):99-107. doi: 10.1080/07315724.2016.1191975. Epub 2016 Oct 31.


Objective: To estimate the association between regular consumption of sweetened soft drinks, natural fruit juice, and coconut water with metabolic syndrome (MetS).

Methods: This was a cross-sectional study including men and women aged 35-74 years from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) Study, excluding patients with type 2 diabetes. The main explanatory variables were beverage consumption and the outcome variable was metabolic syndrome (Adult Treatment Panel III).

Results: After adjustments, a daily intake of 250 ml of soft drink increased the chance of metabolic syndrome (odds ratio [OR] = 1.95; 95% confidence interval [CI], 1.60-2.38). There was no association between coconut water and MetS. Moderate consumption of fruit juices has low odds of MetS compared to no consumption.

Conclusion: Our results add evidence to potential negative effects of sweetened soft drinks on cluster metabolic abnormalities in middle-income countries.

Keywords: metabolic syndrome; obesity; sugar-sweetened soft drinks intake.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Brazil / epidemiology
  • Carbonated Beverages / adverse effects*
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Metabolic Syndrome / chemically induced*
  • Metabolic Syndrome / epidemiology*
  • Middle Aged
  • Odds Ratio
  • Sweetening Agents / adverse effects*


  • Sweetening Agents