Abstract
The EtOH extract of the roots and rhizomes of Clematis mandshurica afforded two new lignans clemomanshurinane C (1) and clemomanshurinane D (2), and three known compounds (3-5). Their structures were elucidated on the basis of spectroscopic means and hydrolysis products. All compounds displayed moderate inhibitory activity against enzyme lipoxygenase.
Keywords:
Clematis mandshurica; Ranunculaceae; lignan; lipoxygenase-inhibiting activiy.
MeSH terms
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Clematis / chemistry*
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology*
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Lignans / chemistry
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Lignans / isolation & purification*
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Lignans / pharmacology*
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Lipoxygenase Inhibitors / chemistry
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Lipoxygenase Inhibitors / isolation & purification*
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Lipoxygenase Inhibitors / pharmacology*
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Plant Roots / chemistry
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Rhizome / chemistry
Substances
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Drugs, Chinese Herbal
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Lignans
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Lipoxygenase Inhibitors
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clemomanshurinane C
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clemomanshurinane D