Serotonin syndrome: Preventing, recognizing, and treating it

Cleve Clin J Med. 2016 Nov;83(11):810-817. doi: 10.3949/ccjm.83a.15129.


As the use of serotonergic agents to treat depression has increased, so too has the incidence of serotonin syndrome. We identify the common agents implicated in serotonin syndrome and the clinical tools to diagnose, manage, and prevent serotonergic toxicity.

Publication types

  • Review

MeSH terms

  • Depression / drug therapy*
  • Humans
  • Medication Therapy Management
  • Serotonin Agents / pharmacology*
  • Serotonin Syndrome* / chemically induced
  • Serotonin Syndrome* / diagnosis
  • Serotonin Syndrome* / prevention & control


  • Serotonin Agents