The SCCS considers 2-phenoxyethanol safe for use as a preservative with a maximum concentration of 1.0%, taking into account the information provided. The toxicokinetics default factor of 4.0 can be reduced to 1.0 yielding a minimum Margin of Safety (MoS) of 25 instead of 100 for the safety assessment of 2-phenoxyethanol. Therefore, the MoS of about 50 for children also covers this specific age group who might be higher exposed to 2-phenoxyethanol than adults. This Opinion does not take into account exposure from sources other than cosmetics.
Keywords: CAS no. 122-99-6; EC no. 204-589-7; Phenoxyethanol; Regulation 1223/2009; SCCS; Scientific opinion.
Copyright Â© 2016 Elsevier Inc. All rights reserved.