Evaluation of antimicrobial activity of glycinate and carbonate derivatives of cholesterol: Synthesis and characterization

Saudi Pharm J. 2016 Nov;24(6):658-668. doi: 10.1016/j.jsps.2015.05.003. Epub 2015 Jun 1.

Abstract

A series of glycinate and carbonate derivatives of cholesterol (4a-t) were synthesized, characterized and assessed for their in vitro antimicrobial activity. Our results revealed that the compounds exerted inhibitory activities against gram-negative bacteria and fungi.

Keywords: Antimicrobial; Carbonate; Cholesterol; Glycinate.