Cardiogenic shock in pregnancy: Analysis from the National Inpatient Sample

Hypertens Pregnancy. 2017 May;36(2):117-123. doi: 10.1080/10641955.2016.1242606. Epub 2016 Nov 11.


Objective: Cardiogenic shock (CS) may occur during pregnancy and dramatically worsen peripartum outcomes.

Methods: We analyzed the National Inpatient Sample from 2002 to 2013 to describe the incidence of, risk factors for and outcomes of CS during pregnancy.

Results: Of the 53,794,192 hospitalizations analyzed, 2044 were complicated by CS. The mortality rate in peripartum women with CS was 18.81% versus 0.02% without. It occurs more often during postpartum (58.83%) as compared with delivery (23.47%) or antepartum (17.70%) hospitalizations. Factors associated with CS -related death included cardiac arrest, renal failure, and sepsis.

Conclusions: CS during pregnancy occurs more commonly in the postpartum period and is associated with a high mortality.

Keywords: Cardiogenic shock; extracorporeal membrane oxygenation; incidence; maternal mortality; pregnancy.

MeSH terms

  • Adolescent
  • Adult
  • Female
  • Humans
  • Incidence
  • Middle Aged
  • Pregnancy
  • Pregnancy Complications / mortality*
  • Retrospective Studies
  • Risk Factors
  • Shock, Cardiogenic / mortality*
  • United States / epidemiology
  • Young Adult