High-throughput and computational approaches for diagnostic and prognostic host tuberculosis biomarkers

Int J Infect Dis. 2017 Mar;56:258-262. doi: 10.1016/j.ijid.2016.10.017. Epub 2016 Nov 9.

Abstract

High-throughput techniques strive to identify new biomarkers that will be useful for the diagnosis, treatment, and prevention of tuberculosis (TB). However, their analysis and interpretation pose considerable challenges. Recent developments in the high-throughput detection of host biomarkers in TB are reported in this review.

Keywords: Biomarker; Gene set enrichment analysis; High-throughput; Tuberculosis.

Publication types

  • Review

MeSH terms

  • Biomarkers*
  • Computational Biology*
  • Humans
  • Prognosis
  • Tuberculosis / diagnosis

Substances

  • Biomarkers