Management of upper gastrointestinal hemorrhage in patients with pseudoxanthoma elasticum

Surgery. 1989 Feb;105(2 Pt 1):170-4.


Pseudoxanthoma elasticum is a rare inherited connective tissue disorder, which exhibits genetic heterogeneity. It is characterized by elastic tissue degeneration involving many organ systems, with typical cutaneous, ocular, arterial, and gastrointestinal manifestations. Upper gastrointestinal tract hemorrhage occurs in 13% of patients with pseudoxanthoma elasticum and is often resistant to conventional methods of treatment. A case report involving gastric hemorrhage in a patient with pseudoxanthoma elasticum is presented. The characteristics of pseudoxanthoma elasticum are reviewed, and the management of upper gastrointestinal tract hemorrhage in these patients is discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Arterioles / pathology
  • Female
  • Gastrointestinal Hemorrhage / etiology
  • Gastrointestinal Hemorrhage / pathology
  • Gastrointestinal Hemorrhage / surgery*
  • Hemostasis, Surgical
  • Humans
  • Pseudoxanthoma Elasticum / complications*
  • Pseudoxanthoma Elasticum / pathology
  • Stomach / blood supply
  • Stomach / pathology
  • Stomach Diseases / etiology
  • Stomach Diseases / pathology
  • Stomach Diseases / surgery*