Fluorescein as an artificial enzyme to mimic peroxidase

Li Liu; Ying Shi; Yufang Yang; Menglu Li; Yijuan Long; Yuming Huang; Huzhi Zheng

doi:10.1039/c6cc07896f

Fluorescein as an artificial enzyme to mimic peroxidase

Chem Commun (Camb). 2016 Nov 24;52(96):13912-13915. doi: 10.1039/c6cc07896f.

Authors

Li Liu¹, Ying Shi², Yufang Yang², Menglu Li², Yijuan Long², Yuming Huang², Huzhi Zheng²

Affiliations

¹ Key Laboratory on Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. ymhuang@swu.edu.cn zhenghz@swu.edu.cn and College of Chemistry and Environmental Science, Qujing Normal University, Qujing, 655011, P. R. China.
² Key Laboratory on Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. ymhuang@swu.edu.cn zhenghz@swu.edu.cn.

PMID: 27841375
DOI: 10.1039/c6cc07896f

Abstract

Fluorescein was found to possess intrinsic peroxidase-like activity, which could catalyze the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) by H₂O₂ to produce a color reaction. It opens the possibility of using such small molecules as peroxidase-like catalysts.

MeSH terms

Catalysis
Fluorescein / chemistry
Fluorescein / metabolism*
Fluorescent Dyes / chemistry
Fluorescent Dyes / metabolism*
Peroxidase / chemistry
Peroxidase / metabolism*

Substances

Fluorescent Dyes
Peroxidase
Fluorescein