Survey of current practices from the International Stereotactic Body Radiotherapy Consortium (ISBRTC) for head and neck cancers

Irene Karam; Min Yao; Dwight E Heron; Ian Poon; Shlomo A Koyfman; Sue S Yom; Farzan Siddiqui; Eric Lartigau; Mustafa Cengiz; Hideya Yamazaki; Wendy Hara; Jack Phan; John A Vargo; Victor Lee; Robert L Foote; K William Harter; Nancy Y Lee; Arjun Sahgal; Simon S Lo

doi:10.2217/fon-2016-0403

Survey of current practices from the International Stereotactic Body Radiotherapy Consortium (ISBRTC) for head and neck cancers

Future Oncol. 2017 Mar;13(7):603-613. doi: 10.2217/fon-2016-0403. Epub 2016 Nov 15.

Authors

Irene Karam¹, Min Yao², Dwight E Heron³, Ian Poon¹, Shlomo A Koyfman⁴, Sue S Yom⁵, Farzan Siddiqui⁶, Eric Lartigau⁷, Mustafa Cengiz⁸, Hideya Yamazaki⁹, Wendy Hara¹⁰, Jack Phan¹¹, John A Vargo³, Victor Lee¹², Robert L Foote¹³, K William Harter¹⁴, Nancy Y Lee¹⁵, Arjun Sahgal¹, Simon S Lo¹⁶

Affiliations

¹ Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Science Center, University of Toronto, Toronto, ON, Canada.
² Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, OH, USA.
³ Department of Radiation Oncology, Otolaryngology, Head & Neck Surgery, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA.
⁴ Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
⁵ Department of Radiation Oncology, University of California, San Francisco, CA, USA.
⁶ Department of Radiation Oncology, Henry Ford Health System, Detroit, MI, USA.
⁷ Department of Radiation Oncology, Centre Oscar Lambret, Lille, France.
⁸ Department of Radiation Oncology, Hacettepe University, Ankara, Turkey.
⁹ Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
¹⁰ Department of Radiation Oncology, Stanford University, Stanford, CA, USA.
¹¹ Department of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA.
¹² Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China.
¹³ Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.
¹⁴ Department of Radiation Oncology, Georgetown University & Vincent T Lombardi Comprehensive Cancer Center, Washington, DC, USA.
¹⁵ Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
¹⁶ Department of Radiation Oncology, University of Washington School of Medicine, Seattle, WA, USA.

PMID: 27842456
DOI: 10.2217/fon-2016-0403

Abstract

Aim: To provide a multi-institutional description of current practices of stereotactic body radiotherapy (SBRT) for head and neck cancer.

Materials & methods: 15 international institutions with significant experience in head and neck SBRT were asked to complete a questionnaire covering clinical and technical factors.

Results: SBRT is used 10-100% of the time for recurrent primary head and neck cancer, and 0-10% of the time in newly diagnosed disease. Five centers use a constraint for primary disease of 3-5 cm and 25-30 cc. Nine institutions apply a clinical target volume expansion of 1-10 mm and 14 use a planning target volume margin of 1-5 mm. Fractionation regimens vary between 15 and 22 Gy in 1 fraction to 30-50 Gy in 5 or 6 fractions. The risk of carotid blowout quoted in the re-irradiation setting ranges from 3 to 20%.

Conclusion: There is considerable heterogeneity in patient selection and techniques in head and neck SBRT practice among experienced centers.

Keywords: SBRT; ablation; head and neck cancer; patterns of practice; stereotactic.

Publication types

Multicenter Study

MeSH terms

Dose Fractionation, Radiation
Female
Follow-Up Studies
Head and Neck Neoplasms / diagnosis
Head and Neck Neoplasms / epidemiology*
Head and Neck Neoplasms / radiotherapy*
Health Care Surveys*
Humans
Male
Neoplasm Staging
Radiation Dosage
Radiosurgery* / adverse effects
Radiosurgery* / methods
Radiotherapy Planning, Computer-Assisted
Standard of Care*