Morning sickness of pregnancy: more than meets the eye

Horm Mol Biol Clin Investig. 2016 Nov 15;30(3):/j/hmbci.2017.30.issue-3/hmbci-2016-0041/hmbci-2016-0041.xml. doi: 10.1515/hmbci-2016-0041.


Wernicke's encephalopathy (WE) is a rare life-threatening complication following severe hyperemesis gravidarum. Early recognition of this condition and prompt thiamine administration is the key to preventing devastating sequelae. We report a successful delivery of a small-for-gestational-age (SGA) baby by a patient with WE and thyrotoxicosis in pregnancy.

Keywords: Wernicke’s encephalopathy (WE); hyperemesis gravidarum; thiamine deficiency.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Birth Weight
  • Female
  • Humans
  • Hyperemesis Gravidarum / complications*
  • Hyperemesis Gravidarum / therapy
  • Infant, Newborn
  • Live Birth
  • Male
  • Pregnancy
  • Thiamine / therapeutic use*
  • Thyrotoxicosis / complications*
  • Thyrotoxicosis / therapy
  • Wernicke Encephalopathy / complications*
  • Wernicke Encephalopathy / therapy


  • Thiamine