Bacteriocin production: a relatively unharnessed probiotic trait?

F1000Res. 2016 Oct 27:5:2587. doi: 10.12688/f1000research.9615.1. eCollection 2016.

Abstract

Probiotics are "live microorganisms which, when consumed in adequate amounts, confer a health benefit to the host". A number of attributes are highly sought after among these microorganisms, including immunomodulation, epithelial barrier maintenance, competitive exclusion, production of short-chain fatty acids, and bile salt metabolism. Bacteriocin production is also generally regarded as a probiotic trait, but it can be argued that, in contrast to other traits, it is often considered a feature that is desirable, rather than a key probiotic trait. As such, the true potential of these antimicrobials has yet to be realised.

Keywords: bacteriocin; gut health; microbiota; probiotic.

Publication types

  • Review

Grants and funding

This work was funded by a Science Foundation Ireland award “Obesibiotics” (11/P1/1137) to PDC.