Effects of delayed cord clamping on the third stage of labour, maternal haematological parameters and acid-base status in fetuses at term

Eur J Obstet Gynecol Reprod Biol. 2016 Dec:207:153-156. doi: 10.1016/j.ejogrb.2016.10.031. Epub 2016 Nov 9.


Objective: To compare the time in the third stage of labour, differences in maternal hematologic parameters 48h after birth and acid-base status in the umbilical cord between the early cord clamping (ECC) and delayed cord clamping (DCC).

Study design: 97 healthy pregnancies at term and a spontaneous vertex delivery at Clinic University Hospital "Virgen de la Arrixaca" (Murcia, Spain), were randomized to ECC group (<10s post-delivery) or to DCC group (2min post-delivery). Duration of the third stage of labour was measured. Samples for acid-base status were taken both from the umbilical artery and vein. Blood samples were taken from the mothers 48h after birth.

Results: No statistical differences were found in the time of the third stage of labour (p=0.35). No statiscally significant differences were found between the number of red cells (p=0.25), hemoglobin (p=0.08) or hematocrit (p=0.15) in mothers. Umbilical acid-base status or gas analysis did not show any differences between the two groups CONCLUSIONS: Delayed cord clamping does not affect significantly the time of the third stage of labour. It does not show either any effect on the hematological parameters in the mother 48h after birth.

Keywords: Acid-base status; Delayed cord clamping; Early cord clamping; Gas analysis; Third stage of labour.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Acid-Base Imbalance / blood
  • Acid-Base Imbalance / epidemiology
  • Acid-Base Imbalance / etiology
  • Acid-Base Imbalance / prevention & control*
  • Adult
  • Erythrocyte Count
  • Female
  • Fetal Blood / chemistry
  • Fetal Distress / blood
  • Fetal Distress / epidemiology
  • Fetal Distress / etiology
  • Fetal Distress / prevention & control*
  • Hematocrit
  • Hemoglobins / analysis
  • Hospitals, University
  • Humans
  • Infant, Newborn
  • Labor Stage, Third*
  • Ligation
  • Male
  • Peripartum Period
  • Pregnancy
  • Risk
  • Spain / epidemiology
  • Term Birth
  • Time Factors
  • Umbilical Cord / surgery*
  • Uterine Hemorrhage / blood
  • Uterine Hemorrhage / epidemiology
  • Uterine Hemorrhage / etiology
  • Uterine Hemorrhage / prevention & control*


  • Hemoglobins