Human papillomavirus vaccines, complex regional pain syndrome, postural orthostatic tachycardia syndrome, and autonomic dysfunction - a review of the regulatory evidence from the European Medicines Agency

Indian J Med Ethics. Jan-Mar 2017;2(1):30-37. doi: 10.20529/IJME.2017.006. Epub 2016 Oct 17.

Abstract

Recent concerns about a possible association between exposure of young women to human papillomavirus (HPV) vaccines and two "dysautonomic syndromes" (a collection of signs and symptoms thought to be caused by autoimmunity) - complex regional pain syndrome (CRPS) and postural orthostatic tachycardia syndrome (POTS) - led the European Medicines Agency (EMA) to review existing evidence. The review was announced by the EMA on July 13, 2015, and was completed on November 4, 2015.

MeSH terms

  • Complex Regional Pain Syndromes
  • Female
  • Humans
  • India
  • Papillomavirus Vaccines*
  • Postural Orthostatic Tachycardia Syndrome*

Substances

  • Papillomavirus Vaccines