Extracorporeal Clearance of Levetiracetam During Continuous Venovenous Hemofiltration in a Critically Ill Patient and New Dosing Recommendation

J Clin Pharmacol. 2017 Apr;57(4):536-537. doi: 10.1002/jcph.844. Epub 2016 Nov 21.

Jos L M L le Noble^{1

2}, Norbert A Foudraine¹, Francois H M Kornips³, Davy G H A van Dam¹, Cees Neef^{4

5}, Paddy K C Janssen^{5

6}

¹ Department of Intensive Care, VieCuri Medical Center, Venlo, The Netherlands.
² Department of Pharmacology and Toxicology, Maastricht University, Maastricht, The Netherlands.
³ Department of Neurology, VieCuri Medical Center, Venlo, The Netherlands.
⁴ CAPHRI School of Public Health and Primary Care Maastricht University, Maastricht, The Netherlands.
⁵ Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Center, Maastricht, The Netherlands.
⁶ Department of Hospital Pharmacy, VieCuri Medical Center, Venlo, The Netherlands.

No abstract available

Keywords: antiepileptic drugs; continuous venovenous hemofiltration; epilepsy; levetiracetam.

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