Characterisation of clinical canine meticillin-resistant and meticillin-susceptible Staphylococcus pseudintermedius in France

Marisa Haenni; Natasha Alves de Moraes; Pierre Châtre; Christine Médaille; Arshnee Moodley; Jean-Yves Madec

doi:10.1016/j.jgar.2014.02.002

Characterisation of clinical canine meticillin-resistant and meticillin-susceptible Staphylococcus pseudintermedius in France

J Glob Antimicrob Resist. 2014 Jun;2(2):119-123. doi: 10.1016/j.jgar.2014.02.002. Epub 2014 Mar 5.

Authors

Marisa Haenni¹, Natasha Alves de Moraes², Pierre Châtre², Christine Médaille³, Arshnee Moodley⁴, Jean-Yves Madec²

Affiliations

¹ Agence Nationale de Sécurité Sanitaire (Anses), Unité Antibiorésistance et Virulence Bactériennes, Lyon, France. Electronic address: marisa.haenni@anses.fr.
² Agence Nationale de Sécurité Sanitaire (Anses), Unité Antibiorésistance et Virulence Bactériennes, Lyon, France.
³ Vebio, Veterinary Laboratory, Arcueil, France.
⁴ Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

PMID: 27873590
DOI: 10.1016/j.jgar.2014.02.002

Abstract

Staphylococcus pseudintermedius is a frequent pathogen in dogs. The emergence of meticillin-resistant S. pseudintermedius (MRSP), which is concomitantly resistant to nearly all veterinary licensed antibiotics used for systemic treatment in dogs, is a major problem for veterinarians. In France, 16.9% (41/243) of the S. pseudintermedius collected in 2010 were MRSP. They mainly belonged to the multiresistant MLST sequence type ST71, spa type t02, SCCmec type II-III (ST71-t02-II-III) European clone. Moreover, we also report the emergence of multiresistant meticillin-susceptible S. pseudintermedius isolates presenting atypical and/or new spa types. This study highlights the need for surveillance, optimised treatment guidelines and new therapeutic alternatives.

Keywords: Antibiotic resistance; Dog; MLST; PFGE; Spa.