Abstract
To determine the contribution of Orientia tsutsugamushi, the agent of scrub typhus, as a cause of acute encephalitis syndrome (AES) in Assam, India, we conducted a retrospective study of hospital patients with symptoms of AES during 2013-2015. Our findings suggest that O. tsutsugamushi infection leads to AES and the resulting illness and death.
Keywords:
AES; Assam; India; Scrub typhus; acute encephalitis syndrome; bacteria; meningitis/encephalitis; vector-borne infections.
MeSH terms
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Acute Febrile Encephalopathy / epidemiology*
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Acute Febrile Encephalopathy / etiology
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Acute Febrile Encephalopathy / microbiology
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Acute Febrile Encephalopathy / mortality
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Antibodies, Bacterial / blood
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Child
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Child, Preschool
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DNA, Bacterial / genetics*
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Female
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Hospitals
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Humans
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India / epidemiology
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Male
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Middle Aged
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Orientia tsutsugamushi / classification
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Orientia tsutsugamushi / genetics*
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Orientia tsutsugamushi / isolation & purification
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Orientia tsutsugamushi / pathogenicity
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Phylogeny*
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Retrospective Studies
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Scrub Typhus / complications
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Scrub Typhus / epidemiology*
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Scrub Typhus / microbiology
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Scrub Typhus / mortality
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Seasons
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Survival Analysis
Substances
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Antibodies, Bacterial
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DNA, Bacterial