Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Nov 21;26(22):R1197-R1203.
doi: 10.1016/j.cub.2016.10.027.

Revisiting Neuronal Cell Type Classification in Caenorhabditis Elegans

Affiliations
Review

Revisiting Neuronal Cell Type Classification in Caenorhabditis Elegans

Oliver Hobert et al. Curr Biol. .

Abstract

We revisit the classification of neuronal cell types in the nervous system of the nematode Caenorhabditis elegans. Based on anatomy and synaptic connectivity patterns, the 302 neurons of the nervous system of the hermaphrodite were categorized into 118 neuron classes more than 30 years ago. Analysis of all presently available neuronal gene expression patterns reveals a remarkable congruence of anatomical and molecular classification and further suggests subclassification schemes. Transcription factor expression profiles alone are sufficient to uniquely classify more than 90% of all neuron classes in the C. elegans nervous system. Neuron classification in C. elegans may be paradigmatic for neuron classification schemes in vertebrate nervous systems.

Similar articles

See all similar articles

Cited by 16 articles

See all "Cited by" articles

Publication types

MeSH terms

Substances

LinkOut - more resources

Feedback