Creating Biological Nanomaterials Using Synthetic Biology

Sci Technol Adv Mater. 2013 Dec 3;15(1):014401. doi: 10.1088/1468-6996/15/1/014401. eCollection 2014 Feb.


Synthetic biology is a new discipline that combines science and engineering approaches to precisely control biological networks. These signaling networks are especially important in fields such as biomedicine and biochemical engineering. Additionally, biological networks can also be critical to the production of naturally occurring biological nanomaterials, and as a result, synthetic biology holds tremendous potential in creating new materials. This review introduces the field of synthetic biology, discusses how biological systems naturally produce materials, and then presents examples and strategies for incorporating synthetic biology approaches in the development of new materials. In particular, strategies for using synthetic biology to produce both organic and inorganic nanomaterials are discussed. Ultimately, synthetic biology holds the potential to dramatically impact biological materials science with significant potential applications in medical systems.

Keywords: Biomaterials; Cellular engineering; Gene circuits; Synthetic biology.

Publication types

  • Review