CHO Cells Can Make More Protein

Sarah W Harcum; Kelvin H Lee

doi:10.1016/j.cels.2016.11.007

CHO Cells Can Make More Protein

Cell Syst. 2016 Nov 23;3(5):412-413. doi: 10.1016/j.cels.2016.11.007.

Authors

Sarah W Harcum¹, Kelvin H Lee²

Affiliations

¹ Department of Bioengineering, Clemson University, 301 Rhodes Research Center, Clemson, SC 29634, USA. Electronic address: harcum@clemson.edu.
² Chemical and Biomolecular Engineering and Delaware Biotechnology Institute, University of Delaware, 15 Innovation Way, Newark, DE 19711, USA.

PMID: 27883886
DOI: 10.1016/j.cels.2016.11.007

Abstract

A new comprehensive genome-scale metabolic model of Chinese hamster ovary cells identifies pathways for improving biopharmaceutical protein production.

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MeSH terms

Animals
CHO Cells*
Clone Cells
Cricetinae
Cricetulus*
Genome
HEK293 Cells
Protein Conformation
Protein Engineering
Protein Phosphatase 1
Recombinant Proteins

Substances

Recombinant Proteins
Protein Phosphatase 1