Effect of mechanical debridement with adjunct antimicrobial photodynamic therapy in the treatment of peri-implant diseases in type-2 diabetic smokers and non-smokers

Photodiagnosis Photodyn Ther. 2017 Mar:17:111-114. doi: 10.1016/j.pdpdt.2016.11.005. Epub 2016 Nov 21.

Abstract

Objective: The aim of the present 6-month follow-up study was to assess the effect of mechanical debridement (MD) with adjunct antimicrobial photodynamic therapy (aPDT) in the treatment of peri-implant diseases in type-2 diabetic smokers and non-smokers.

Methods: Patients were divided into 2 groups: (a) Group-1: type-2 diabetic smokers; and (b) Group-2: type-2 diabetic non-smokers. In both groups, hemoglobin A1c (HbA1c) levels and peri-implant bleeding on probing (BOP) and probing depth (PD) ≥4mm were measured at baseline and after 6 months of follow-up. Group comparisons were performed using the Kruskall-Wallis test and for multiple comparisons Bonferroni post hoc test was used. Level of significance was set at P<0.05.

Results: Sixty-four individuals (33 in Group-1 and 31 in Group-2) were included. At baseline, BOP and PD≥4mm were comparable among individuals in groups 1 and 2. The mean age of individuals in groups 1 and 2 were 52.6±0.8 and 54.4±1.2years, respectively. The mean duration of type-2 DM among patients in groups 1 and 2 was 8.2±0.3years and 10±0.2years, respectively. In Group-1, the participants were smoking 6.3±1.5 cigarettes daily since 12.7±3.3years. At 6-months follow-up, there was no statistically significant difference in BOP and PD≥4mm among patients in groups 1 and 2 compared with the respective baseline values. HbA1c levels were comparable in all groups at all time intervals CONCLUSION: Outcomes of the treatment of periimplant diseases using MD with adjunct aPDT are comparable among type-2 diabetic smokers and non-smokers.

Keywords: Bleeding on probing; Gingival inflammation; Non-surgical periimplant therapy; Probing depth; Type-2 diabetes mellitus.

MeSH terms

  • Age Factors
  • Combined Modality Therapy
  • Debridement / methods*
  • Diabetes Mellitus, Type 2 / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Peri-Implantitis / drug therapy*
  • Peri-Implantitis / epidemiology
  • Photochemotherapy / methods*
  • Photosensitizing Agents / therapeutic use*
  • Smoking / epidemiology

Substances

  • Photosensitizing Agents