Cardiac Disease Associated with Human Immunodeficiency Virus Infection

Cardiol Clin. 2017 Feb;35(1):59-70. doi: 10.1016/j.ccl.2016.09.003.


Over the last 2 decades human immunodeficiency virus (HIV) infection has become a chronic disease requiring long-term management. Aging, antiretroviral therapy, chronic inflammation, and several other factors contribute to the increased risk of cardiovascular disease in patients infected with HIV. In low-income and middle-income countries where antiretroviral therapy access is limited, cardiac disease is most commonly related to opportunistic infections and end-stage manifestations of HIV/acquired immunodeficiency syndrome, including HIV-associated cardiomyopathy, pericarditis, and pulmonary arterial hypertension. Cardiovascular screening, prevention, and risk factor management are important factors in the management of patients infected with HIV worldwide.

Keywords: Cardiovascular diseases/epidemiology; Cardiovascular diseases/management; HIV infections/Complications; Human immunodeficiency virus.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases* / diagnosis
  • Cardiovascular Diseases* / epidemiology
  • Cardiovascular Diseases* / etiology
  • Global Health
  • HIV Infections / complications*
  • HIV Infections / epidemiology
  • HIV*
  • Humans
  • Incidence
  • Risk Factors