Update on the Management of Central Retinal Artery Occlusion

Neurol Clin. 2017 Feb;35(1):83-100. doi: 10.1016/j.ncl.2016.08.013.


Central retinal artery occlusion (CRAO) is caused by partial or complete occlusion of the central retinal artery, most commonly by an embolus from the ipsilateral carotid artery, aortic arch, or heart, and is the ocular equivalent of an acute cerebral ischemic event. The risk factors for a CRAO and acute cerebral ischemia are very similar, if not identical. Because no current therapeutic intervention has been shown to improve visual outcomes compared with the natural history of CRAO, management of CRAO should be focused on secondary prevention of vascular events, such as cerebral ischemia, myocardial infarction, and cardiovascular death.

Keywords: Branch retinal artery occlusion; Central retinal artery occlusion; Ischemia; Management; Stroke; Thrombolysis; Treatment.

Publication types

  • Review
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cerebral Infarction / complications*
  • Humans
  • Retinal Artery Occlusion* / complications
  • Retinal Artery Occlusion* / diagnosis
  • Retinal Artery Occlusion* / etiology
  • Retinal Artery Occlusion* / therapy
  • Risk Factors