Wet Wrap Therapy in Moderate to Severe Atopic Dermatitis

Immunol Allergy Clin North Am. 2017 Feb;37(1):123-139. doi: 10.1016/j.iac.2016.08.003. Epub 2016 Nov 1.


National and international guidelines address stepwise atopic dermatitis (AD) management. Wet wrap therapy (WWT) is important as an acute therapeutic intervention for treatment of moderate to severe AD. Using clothing instead of bandages makes this intervention simpler, less time intensive, and less expensive. Education of patients and caregivers is critical to success; methodology must be standardized. Future studies must carefully describe all procedure components. Incorporation of validated outcomes tools would help with interpretation. WWT should be considered as a potential treatment option ahead of systemic immunosuppressive therapies for patients failing conventional therapy.

Keywords: Atopic dermatitis; Atopic eczema; Occlusion therapy; Occlusive dressings; Wet dressings; Wet wrap; Wet wrap therapy.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Bandages / statistics & numerical data*
  • Dermatitis, Atopic / therapy*
  • Disease Progression
  • Humans
  • Occlusive Dressings / statistics & numerical data*
  • Practice Guidelines as Topic


  • Adrenal Cortex Hormones