The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community

Genome Biol. 2016 Nov 25;17(1):239. doi: 10.1186/s13059-016-1103-0.


Nanopore DNA strand sequencing has emerged as a competitive, portable technology. Reads exceeding 150 kilobases have been achieved, as have in-field detection and analysis of clinical pathogens. We summarize key technical features of the Oxford Nanopore MinION, the dominant platform currently available. We then discuss pioneering applications executed by the genomics community.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms*
  • Aneuploidy
  • Computational Biology / instrumentation
  • Computational Biology / methods*
  • DNA / analysis
  • DNA / genetics
  • Genomics / instrumentation
  • Genomics / methods*
  • High-Throughput Nucleotide Sequencing / instrumentation
  • High-Throughput Nucleotide Sequencing / methods*
  • Humans
  • Nanopores*
  • Reproducibility of Results


  • DNA