Treating Scars on the Oral Mucosa

Facial Plast Surg Clin North Am. 2017 Feb;25(1):89-97. doi: 10.1016/j.fsc.2016.08.008.


Mucosal wounds tend to heal more rapidly than skin wounds and with minimal to no scar formation and hence have a minimal impact on function or aesthetics. This is likely due to differences in the magnitude and timing of the various factors that contribute to wound healing. Some examples of these differences are fibroblast proliferation, transforming growth factor-β, macrophages, neutrophils, and T cells. Other factors, such as the moist environment, contribute to the favorable wound-healing characteristics of mucosa.

Keywords: Epithelium; Fibroblast; Mucosa; Scar; Skin; TGF-β; Wound.

Publication types

  • Review

MeSH terms

  • Cicatrix / etiology
  • Cicatrix / surgery*
  • Humans
  • Mouth Diseases / complications
  • Mouth Mucosa* / injuries
  • Mouth Mucosa* / pathology
  • Mouth Mucosa* / physiology
  • Mouth Mucosa* / surgery
  • Postoperative Complications / surgery
  • Reconstructive Surgical Procedures / methods*