HIV Vaccines: One Step Closer

Michael Sze Yuan Low; David Tarlinton

doi:10.1016/j.molmed.2016.10.006

HIV Vaccines: One Step Closer

Trends Mol Med. 2017 Jan;23(1):1-3. doi: 10.1016/j.molmed.2016.10.006. Epub 2016 Nov 23.

Authors

Michael Sze Yuan Low¹, David Tarlinton²

Affiliations

¹ Immunology Division, Walter and Eliza Hall Institute of Medical Research, University of Melbourne, 1G Royal Parade, Parkville, Victoria, Australia; Department of Haematology, Monash Health, Monash Hospital, 246 Clayton Road Clayton, Victoria, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria, Australia; Department of Immunology and Pathology, Monash University, Melbourne, Victoria 3004, Australia.
² Department of Immunology and Pathology, Monash University, Melbourne, Victoria 3004, Australia. Electronic address: david.tarlinton@monash.edu.

PMID: 27889424
DOI: 10.1016/j.molmed.2016.10.006

Abstract

Currently there is no effective vaccine against human immunodeficiency virus (HIV). Four recently published studies in Cell and Immunity now show that using planned sequential boosting with antigens to guide the humoral response towards broadly neutralizing antibodies could provide a solution to achieving vaccination against HIV-1.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

AIDS Vaccines / immunology*
AIDS Vaccines / pharmacology
AIDS Vaccines / therapeutic use
Animals
Antibodies, Neutralizing / immunology*
HIV Antibodies / immunology*
HIV Infections / immunology*
HIV Infections / prevention & control*
HIV Infections / virology
HIV-1 / immunology*
Humans
Vaccination

Substances

AIDS Vaccines
Antibodies, Neutralizing
HIV Antibodies