Fluid Supplementation versus No Fluid Supplementation in Late Preterm and Term Neonates with Asymptomatic Polycythemia: A Randomized Controlled Trial

Mangalabharathi Sundaram; Sourabh Dutta; Anil Narang

doi:10.1007/s13312-016-0972-3

Fluid Supplementation versus No Fluid Supplementation in Late Preterm and Term Neonates with Asymptomatic Polycythemia: A Randomized Controlled Trial

Indian Pediatr. 2016 Nov 15;53(11):983-986. doi: 10.1007/s13312-016-0972-3.

Authors

Mangalabharathi Sundaram¹, Sourabh Dutta, Anil Narang

Affiliation

¹ Division of Neonatology, Department of Pediatrics, PGIMER, Chandigarh, India. Correspondence to: Dr Mangalabharathi Sundaram, Division of Neonatology, Departments of Pediatrics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. drmangalabharathi@gmail.com.

PMID: 27889725
DOI: 10.1007/s13312-016-0972-3

Abstract

Objective: To compare supplemental intravenous fluids with no supplementation in asymptomatic polycythemic late preterm and term neonates.

Methods: 55 infants with venous haematocrit of 65-75 were randomly allocated to receive either 25 mL/kg IV normal saline over 6-8 hours or routine fluids. They were followed up for 48 hours.

Results: There was no significant difference between fluid supplementation and control groups regarding need for partial exchange transfusion [6/27 (22.2%) vs 8/28 (28.6%); P=0.59].

Conclusion: We did not find any evidence of clinical benefit with IV fluid supplementation in late preterm and term neonates with asymptomatic polycythemia (PCV 65-75).

Publication types

Randomized Controlled Trial

MeSH terms

Asymptomatic Diseases / therapy
Exchange Transfusion, Whole Blood*
Female
Fluid Therapy*
Humans
Infant, Newborn
Infant, Newborn, Diseases / therapy*
Infant, Premature
Male
Polycythemia / therapy*