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, 6 (5), 423-429

Comparative Evaluation of the Efficacy of Fluoride Varnish and Casein Phosphopeptide - Amorphous Calcium Phosphate in Reducing Streptococcus mutans Counts in Dental Plaque of Children: An in vivo Study

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Comparative Evaluation of the Efficacy of Fluoride Varnish and Casein Phosphopeptide - Amorphous Calcium Phosphate in Reducing Streptococcus mutans Counts in Dental Plaque of Children: An in vivo Study

Shweta Chandak et al. J Int Soc Prev Community Dent.

Abstract

Aim: To assess the comparative efficacy of fluoride varnish and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) complex visa viz. Streptococcus mutans in plaque, and thereby the role that these two agents could play in the prevention of dental caries.

Materials and methods: A cluster sample of 120 caries inactive individuals belonging to moderate and high caries risk group were selected from 3-5-year-old age group based on the criteria given by Krassee and were randomized to four groups, namely, fluoride varnish - Group I, CPP-ACP complex - Group II, mixture of CPP-ACP complex -Gourp III, and fluoride and routine oral hygiene procedures as control - Group IV. The results thus obtained were analyzed using Statistical Package for the Social Sciences (SPSS) version 16.

Results: A statistically significant difference in the pre and post-application scores of S. mutans (P < 0.01) count was observed in all the groups with CPP-ACP plus fluoride group being the most proficient.

Conclusion: Materials such as fluoride varnish, CPP-ACP, and CPP-ACP plus fluoride protects the tooth structure, preserving the integrity of primary dentition, with the most encouraging results being with CPP-ACP plus fluoride.

Keywords: Casein phosphopeptide–amorphous calcium phosphate (CPP–ACP); Streptococcus mutans; fluoride varnish.

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