Novel Organic Synthesis through Ultrafast Chemistry

Angew Chem Int Ed Engl. 2017 Jan 16;56(3):682-684. doi: 10.1002/anie.201609595. Epub 2016 Nov 28.

Abstract

How fast are flashes? The field of flow chemistry has recently received increasing attention owing to the availability of commercial flow equipment. New syntheses with very short-lived intermediates have been enabled by sub-millisecond mixing and reaction regimes in tailor-made flow devices.

Keywords: Fries rearrangement; flash chemistry; flow chemistry; microreactors; organolithium compounds.