Thrombophlebitis migrans following co-trimoxazole therapy

Postgrad Med J. 1989 Jan;65(759):51-2. doi: 10.1136/pgmj.65.759.51.


We report an unusual and severe vasculitic disorder following co-trimoxazole, given orally for a urinary tract infection. The vasculitis was manifest solely as thrombophlebitis migrans and involving only veins without evidence of polyarteritis nodosa, or underlying malignancy.

Publication types

  • Case Reports

MeSH terms

  • Anti-Infective Agents, Urinary / adverse effects*
  • Drug Combinations / adverse effects
  • Humans
  • Male
  • Middle Aged
  • Sulfamethoxazole / adverse effects*
  • Thrombophlebitis / chemically induced*
  • Trimethoprim / adverse effects*
  • Trimethoprim, Sulfamethoxazole Drug Combination


  • Anti-Infective Agents, Urinary
  • Drug Combinations
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Trimethoprim
  • Sulfamethoxazole