Two clinical experiments were conducted to study the effect of kVp and mAs on resolution and on image contrast percentage. The resolution was measured with a "test pattern." By using a transmission densitometer, image contrast percentage was determined by a mathematical formula. In the first part of the experiment, the density of the film was kept constant by changing the kVp and mAs. In the second part of the experiment, different mAs's were chosen, and for each mAs, several kVp's were used. Five observers read the radiographs. The first experiment showed that, when the film density is kept constant, the higher the kVp, the lower the resolution and image contrast percentage; also, the higher the mAs, the higher the resolution and image contrast percentage. The second experiment showed that when the film density is not kept constant, the correlation between kVp and resolution and between kVp and image contrast percentage was the same as in the first experiment. However, there was negligible correlation between mAs and resolution and between mAs and image contrast percentage. A high positive correlation was found between resolution and image contrast percentage, but a high negative correlation was found between resolution and film density.