An update on larynx cancer

CA Cancer J Clin. 2017 Jan;67(1):31-50. doi: 10.3322/caac.21386. Epub 2016 Nov 29.


Answer questions and earn CME/CNE Laryngeal cancer remains one of the most common tumors of the respiratory tract. Fortunately, significant advancements have been made over the past decade in the treatment of laryngeal cancer. Although surgery has been the historical mainstay for localized disease and still is an integral part of treatment, nonsurgical options like radiation and systemic therapy have emerged as viable options. In addition, in the metastatic setting, novel agents are showing promise for this patient population. The care for patients with laryngeal cancer continues to evolve and truly requires a multidisciplinary team-based approach. Unique morbidities, such as loss of natural voice, respiration, and airway protection during swallowing, are observed with this disease and require special consideration. CA Cancer J Clin 2017;67:31-50. © 2016 American Cancer Society.

Keywords: cancer; laryngeal preservation; larynx; multimodality; squamous cell carcinoma.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Incidence
  • Laryngeal Neoplasms / diagnosis*
  • Laryngeal Neoplasms / epidemiology
  • Laryngeal Neoplasms / therapy*
  • Male
  • Patient Care Team
  • Racial Groups / statistics & numerical data
  • Risk Factors
  • Sex Distribution
  • Survival Rate
  • United States / epidemiology