ANOS1: a unified nomenclature for Kallmann syndrome 1 gene (KAL1) and anosmin-1

Brief Funct Genomics. 2017 Jul 1;16(4):205-210. doi: 10.1093/bfgp/elw037.

Abstract

It is accepted that confusion regarding the description of genetic variants occurs when researchers do not use standard nomenclature. The Human Genome Organization Gene Nomenclature Committee contacted a panel of consultants, all working on the KAL1 gene, to propose an update of the nomenclature of the gene, as there was a convention in the literature of using the 'KAL1' symbol, when referring to the gene, but using the name 'anosmin-1' when referring to the protein. The new name, ANOS1, reflects protein name and is more transferrable across species.

Keywords: : Kallmann; ANOS1; KAL1; anosmin-1; gene; nomenclature.

MeSH terms

  • Animals
  • Extracellular Matrix Proteins / chemistry
  • Extracellular Matrix Proteins / genetics*
  • Extracellular Matrix Proteins / metabolism
  • Humans
  • Kallmann Syndrome / genetics*
  • Nerve Tissue Proteins / chemistry
  • Nerve Tissue Proteins / genetics*
  • Nerve Tissue Proteins / metabolism
  • Terminology as Topic*

Substances

  • ANOS1 protein, human
  • Extracellular Matrix Proteins
  • Nerve Tissue Proteins