Abstract
Cytogenetic studies of two uterine leiomyomas from the same patient revealed different karyotypic changes. Both tumors showed only a single chromosome abnormality; one had t(1;6)(q23;p21) and the other del(7)(q21.2q31.2). These findings support the view that multiple leiomyomas of the uterus arise independently.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Chromosome Deletion*
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Chromosomes, Human, Pair 1
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Chromosomes, Human, Pair 6
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Chromosomes, Human, Pair 7
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Female
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Genetic Markers
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Humans
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Karyotyping
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Leiomyoma / genetics*
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Leiomyoma / pathology
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Middle Aged
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Neoplasms, Multiple Primary / genetics*
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Neoplasms, Multiple Primary / pathology
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Translocation, Genetic*
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Uterine Neoplasms / genetics*
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Uterine Neoplasms / pathology