Different karyotypic abnormalities, t(1;6) and del(7), in two uterine leiomyomas from the same patient

Cancer Genet Cytogenet. 1989 Oct 1;42(1):51-3. doi: 10.1016/0165-4608(89)90007-1.

Abstract

Cytogenetic studies of two uterine leiomyomas from the same patient revealed different karyotypic changes. Both tumors showed only a single chromosome abnormality; one had t(1;6)(q23;p21) and the other del(7)(q21.2q31.2). These findings support the view that multiple leiomyomas of the uterus arise independently.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Deletion*
  • Chromosomes, Human, Pair 1
  • Chromosomes, Human, Pair 6
  • Chromosomes, Human, Pair 7
  • Female
  • Genetic Markers
  • Humans
  • Karyotyping
  • Leiomyoma / genetics*
  • Leiomyoma / pathology
  • Middle Aged
  • Neoplasms, Multiple Primary / genetics*
  • Neoplasms, Multiple Primary / pathology
  • Translocation, Genetic*
  • Uterine Neoplasms / genetics*
  • Uterine Neoplasms / pathology

Substances

  • Genetic Markers