Antibiotic Exposure and Risk for Death or Bronchopulmonary Dysplasia in Very Low Birth Weight Infants

J Pediatr. 2017 Feb;181:289-293.e1. doi: 10.1016/j.jpeds.2016.11.002. Epub 2016 Nov 28.


We assessed the association between antibiotic exposure in the first 2 weeks of life and development of bronchopulmonary dysplasia in a cohort of very low birth weight infants. After controlling for the severity of illness, each additional day of antibiotic therapy was associated with both an increased risk for and severity of bronchopulmonary dysplasia.

Keywords: Neonatal intensive care unit; Neonate.

MeSH terms

  • Anti-Bacterial Agents / adverse effects*
  • Bronchopulmonary Dysplasia / etiology*
  • Bronchopulmonary Dysplasia / mortality
  • Cohort Studies
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Very Low Birth Weight
  • Intensive Care Units, Neonatal
  • Male
  • Retrospective Studies
  • Risk Factors


  • Anti-Bacterial Agents